604: Proteomic profile of amniotic fluid exosomes in spontaneous preterm birth
نویسندگان
چکیده
منابع مشابه
Proteomic Analysis of Early Mid-Trimester Amniotic Fluid Does Not Predict Spontaneous Preterm Delivery
OBJECTIVE The aim of this study was to identify early proteomic biomarkers of spontaneous preterm delivery (PTD) in mid-trimester amniotic fluid from asymptomatic women. METHODS This is a case-cohort study. Amniotic fluid from mid-trimester genetic amniocentesis (14-19 weeks of gestation) was collected from 2008 to 2011. The analysis was conducted in 24 healthy women with subsequent spontaneo...
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INTRODUCTION The aim of this study was to investigate neutrophil elastase (NE) in amniotic fluid as a potential marker for predicting pregnancy continuation. MATERIAL AND METHODS We enrolled 34 pregnant women with bulging fetal membrane during the second trimester who underwent emergent cerclage after confirming the absence of intrauterine infection (amniotic fluid glucose ≥15 mg/dL). Amnioti...
متن کاملMid-Trimester Amniotic Fluid High Sensitive C-Reactive Protein Level in the Prediction of Preterm Delivery
Background and Objectives: Preterm labor is a serious problem in obstetrics, accounting for 70% of perinatal mortality. High sensitive C - reactive protein (HS-CRP) is a sensitive marker of Inflammation. Our aim in this study was to determine Amniotic fluid hs-CRP concentration and its correlation with pre-Term delivery. Materials and methods: This prospective study was conducted on 90 p...
متن کاملPreterm birth: prediction by alkaline Phosphatase, ferritin and alpha-fetoprotein in amniotic fluid
Objective Preterm labor is a common health problem with has very serious adverse effects and burden of cost. Early diagnosis of preterm labor may be useful for prevention of its adverse effects. The aim of the present study was to evaluate levels of alkaline phosphatase (ALP), ferritin, and alpha-fetoprotein (AFP) in amniotic fluid in the second trimester of pregnant women for predicting preter...
متن کاملMultidimensional Proteomics Analysis of Amniotic Fluid to Provide Insight into the Mechanisms of Idiopathic Preterm Birth
BACKGROUND Though recent advancement in proteomics has provided a novel perspective on several distinct pathogenetic mechanisms leading to preterm birth (inflammation, bleeding), the etiology of most preterm births still remains elusive. We conducted a multidimensional proteomic analysis of the amniotic fluid to identify pathways related to preterm birth in the absence of inflammation or bleedi...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2018
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2017.11.132